279 patients with thyroid adules were analysed, who had undergone on operaition at the Department of Surgery, Chungnam National University Hospital, over a period of 6 years form January 1989 unit December 1994.
@ES The results were as follow:
@EN 1) 171 cases(61.3%) were benign and 108 cases(38.7%) were malignant.
2) The ratio of male to female was 1:6.3; for benign nodules; it was 1:87, for malignant nodules it was 1:4.4.
3) Thyroid nodules were more prevalent in 3rd the decade, both benign as well as malignant diseases.
4) The most common clinical manifestation was the presence of a palpable mass(100%), followed by palpitation, fatigue and heat intolerance in order of frequency.
5) As to the duration of illness, 35.1% of cases were within 3 months, 64.3% of cases within 1 year.
6) In 83.2% of cases, the nodules were unilateral; 48.2% on right, 35.1% the left.
7) 83.0% of the benign tumors and 79.6% of the malignant tumors were solitary; and 48.0% of the benign tumors and 86.1% of the malignant ones were solid.
8) 2~3cm was the most common(37.3%) size nodule and 71.7% were under 4cm in diameter.
9) In scintigraphy, 83.6% of the benign nodules and 94.4% of the malignant ones were cold nodules. In thyroid I131 uptake test, 87.8% were within normal limit(87.1% benign and 96.3% malignant).
10) Among the benign nodules, adenomatous goiter(73.1%) was most prevalent, followed by adenoma(14.6%), Graves' disease(7.6%) simple cyst(2.9%), Hashimoto's thyroiditis(1.2%), and subacute thyroiditis (0.6%). In the malignant nodule, papillary
carcinoma was most prevalent(73.1%), followed by follicular carcinoma(20.4%), medullary carcinoma(3.7%) and anaplastic carcinoma(0.9%).
11) Benign tumors were treated most frequently by lobectomy(77.2%), followed by total thyroidectomy(14.0%), near total thyroidectomy(5.3%), and lobectomy with isthemectomy(3.5%).
Malignant thyroid nodules were treated by lobectomy(44.4%), total thyroidectomy(21.3%), lobectomy with isthmectomy (13.0%), near total thyroidectomy(5.6%); and 15.7% of cases underwent radical neck dissection.
12) The most common postoperative complication was transient hypocalcemia(5.4%), followed by permanent hypocalcemia(2.5%), and transient hoarsness(2.5%)
|